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Next, we investigated the level of compression of Cronos in the heart and musculoskeletal muscles of zebra fish at different stage of maturation using in vitro hybridisation (Figure 6A) and real-time PCR (Figure 6B). The cronos is highly expressive in the boneskeletal muscles of the fish during maturation (ratio:1 of cronos to whole-length ttna), but falls off strongly in adults (ratio:70).
Though the Cronos term in the Zebra Fish breast also seems to be evolutionary, it is much lower than in the musculoskeletal system, with a relationship of hpf:5 at 72_?hpf and hff:1:30 in adult life. The low level of cardio Cronos manifestation (coupled with a low level of involvement of ttnb in zebra fish hearts) is probably one of the reasons for the serious and undistinguishable cardio sarcoma disorder in n/n and c/c gene variants.
Seeing that the main finding that prompted this work was the variability in phenotypic gravity in cardiomyopathic heart disease sufferers, we next checked whether there was any significant Cronos gene expression found in heart mammals. The Cronos values were found to be much higher in the development of murine heart than in zebra fish, with almost the same full-length transcription values of Cronos and Ttn (Figure 6C) on 12.5 foetal days.
From cronos to ?-30% of full-length titin. Depending on progression and in different muscular bed, the articulation of the musculature of the skeleton may vary with a 1:5 relationship in the hindquarters of the mice at P2 and a 1:16 to:1000 relationship in the mature stretching muscles digititorum langus (rapid twitching) or soleus to ?:1000 (slow twitching).
Specifically, the open issue is whether all abbreviations of DDN result in myocardial or skeletal muscular phenomena or, vice versa, whether DDN abbreviations have no effect on myocardial or skeletal muscular phenomena. It is found only in the Novex-3 isolate, which is low level express in the HRH (